Author

Sumit Kar

Revolution Medicines (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Aaliyah Washington· 1 shared Alberto VidesiD· 1 shared Alexander I. SpiraiD· 1 shared Antonio Cuevas-NavarroiD· 1 shared Aparna HegdeiD· 1 shared Arvin C. DariD· 1 shared Ben SangiD· 1 shared Brian Matthew WolpiniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Aaliyah Washington

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Mechanisms of resistance to active state selective tri-complex RAS inhibitors

Ben Sang, Ling Feng Ye, Feng Hu, Yasin Pourfarjam, Antonio Cuevas-Navarro, Shijie Fan, Zheng Qing Fu, Aaliyah Washington, Diego J. Rodriguez, Alberto Vides, Sumit Kar, Ethan Ahler, Kevin K. Lin, Aparna Hegde, Jacqueline A.M. Smith, , Piro Lito

This study identifies mechanisms of resistance to tri-complex RAS inhibitors in patients with RAS-driven cancers, showing that resistance alterations disrupt the RAS:drug:CYPA tri-complex formation.

bioRxiv · Apr 24, 2025 · PreprintCancer Biology