MNRR1 is required for Triple Negative Breast Cancer growth and metastasis and can be targeted by repurposed drugs.
Mrunal Sathe, Paige M. Minchella, Caleb Vegh, Mithra Modikuppam Dharmalingam, Vignesh Pasupathi, Yue Xi, Sagarika Rai, Mrunmayee Patil, Habiba Elshenawy, Sydney Rudolph, Gaurav Bhatti, Adi Laurentiu Tarca, Neeraja Purandare, Andrew M. Fribley, Lawrence I. Grossman, Siddhesh Aras
This study identifies MNRR1 as a critical driver of TNBC growth and metastasis, showing it can be targeted by existing drugs.
bioRxiv · Feb 3, 2026 · PreprintCancer Biology