Sensitization of knee-innervating sensory neurons by tumor necrosis factor-α activated fibroblast-like synoviocytes: an in vitro, co-culture model of inflammatory pain
Sampurna Chakrabarti, Zoe Lee Hore, Luke A. Pattison, Sylvine Lalnunhlimi, Charity N. Bhebhe, Gerard Callejo, David Colin Bulmer, Leonie S. Taams, Franziska Denk, Ewan St. John Smith
This study shows that TNF-α activated fibroblast-like synoviocytes sensitize knee neurons in vitro, contributing to inflammatory pain in arthritis.
Pain · Apr 22, 2020Peer-reviewedNeuroscience