Author
University of Cambridge
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Katie J Williams, Giulia Galimberti, James P. Higham…·David Colin Bulmer
This study identifies MMP3, MMP8, and MMP9 as inducers of Ca2+ release in DRG neurons via PAR1 and PLC activation, revealing a novel role for MMP signaling in sensory neurons during inflammation.
James P. Higham, Charity N. Bhebhe, Rohit A Gupta…·David Colin Bulmer
This study identifies Angiotensin II as a pro-nociceptive mediator in IBD by showing increased Agt expression and AT1 receptor activation in colonic neurons.
Charity N. Bhebhe, James P. Higham, Rohit A Gupta…·David Colin Bulmer
The paper shows that KV7 channel openers, but not SK/IK channel openers, reduce colonic afferent responses to noxious stimuli, suggesting KV7 channels as potential targets for abdominal pain treatment.
Sampurna Chakrabarti, Zoe Lee Hore, Luke A. Pattison…·Ewan St. John Smith
This study shows that TNF-α activated fibroblast-like synoviocytes sensitize knee neurons in vitro, contributing to inflammatory pain in arthritis.