Author

T. Aguirre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Schuetz· 1 shared C. Seyffarth· 1 shared D. Fiedler· 1 shared G. L. Dornan· 1 shared J. P. von Kries· 1 shared M. Neuenschwander· 1 shared S. Hostachy· 1 shared V. Haucke· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

A. Schuetz

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1 paper

Recent·Most cited

An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor

T. Aguirre, G. L. Dornan, S. Hostachy, M. Neuenschwander, C. Seyffarth, V. Haucke, A. Schuetz, J. P. von Kries, D. Fiedler

The paper identifies FMP-201300 as a potent and selective inhibitor for IP6K1 and IP6K2 with a valine gatekeeper mutation, revealing an allosteric mechanism of action.

bioRxiv · Apr 26, 2023Biochemistry