Author

A. Schuetz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cell Biology· 1 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1

Frequent Co-Authors

J. Ananworanich· 2 shared M. de Souza· 2 shared A. Dwivedi· 1 shared A. Giannakopulos· 1 shared A. Hakimi· 1 shared A. Kholomeev· 1 shared A. Kreutzmann· 1 shared A. Kuehn· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

J. Ananworanich

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Unravelling ATP processing by the AAA+ protein p97 at the atomic level

M. Shein, M. Hitzenberger, T. Cheng, S. Rout, K. Leitl, Y. Sato, M. Zacharias, E. Sakata, A. Schuetz

This study uses cryo-EM, NMR, and MD simulations to reveal the atomic-level mechanism of ATP processing by p97, identifying a metastable ADP.Pi state and its role in coordinating subunit actions.

bioRxiv · Aug 26, 2023Biophysics

Parallelized Acquisition of Orbitrap and Astral Analyzers Enables High-Throughput Quantitative Analysis.

H. Stewart, D. Grinfeld, A. Giannakopulos, J. Petzoldt, T. Shanley, M. Garland, E. Denisov, A. Peterson, E. Damoc, M. Zeller, T. Arrey, A. Pashkova, S. Renuse, A. Hakimi, A. Kuehn, , C. Hock

The paper introduces a new hybrid mass spectrometer combining Orbitrap and Astral analyzers to enable faster and more sensitive high-resolution accurate mass MS/MS spectra acquisition for proteomics.

bioRxiv · Jun 2, 2023Cell Biology

An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor

T. Aguirre, G. L. Dornan, S. Hostachy, M. Neuenschwander, C. Seyffarth, V. Haucke, A. Schuetz, J. P. von Kries, D. Fiedler

The paper identifies FMP-201300 as a potent and selective inhibitor for IP6K1 and IP6K2 with a valine gatekeeper mutation, revealing an allosteric mechanism of action.

bioRxiv · Apr 26, 2023Biochemistry

Productive and latent HIV infections originate in resting CD4+ T cells

S. Wietgrefe, J. Anderson, L. Duan, P. J. Southern, P. Zuck, G. Wu, B. Howell, C. Reilly, E. Kroon, S. Chottanapund, S. Buranapraditkun, C. Sacdalan, N. Tulmethakaan, D. J. Colby, N. Chomchey, , A. T. Haase

This study shows that resting CD4+ T cells are the initial source of both productive and latent HIV infections in the earliest stages of detectable infection.

bioRxiv · Aug 26, 2022 · PreprintImmunology

Monocyte Infection Dynamics Shape HIV-1 Phyloanatomy in the Peripheral Blood

B. Rife Magalis, S. L. Strickland, S. D. Shank, P. Autissier, A. Schuetz, P. Sithinamsuwam, S. Lerdlum, J. L. K. Fletcher, M. de Souza, J. Ananworanich, V. Valcour, K. C. Williams, S. L. Kosakovsky Pond, S. Ratto Kim, M. Salemi, SEARCH007

This study shows that HIV-1 evolves differently in monocytes compared to T cells, suggesting monocytes may be a significant viral reservoir.

bioRxiv · Dec 12, 2018 · PreprintEvolutionary Biology