Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
M. Brenner, C. Zink, L. Witzinger…·A. Gohla
This study identifies 7,8-dihydroxyflavone as a direct inhibitor of pyridoxal phosphatase, increasing PLP levels in mouse hippocampal neurons and validating PDXP as a druggable target.
T. Aguirre, G. L. Dornan, S. Hostachy…·D. Fiedler
The paper identifies FMP-201300 as a potent and selective inhibitor for IP6K1 and IP6K2 with a valine gatekeeper mutation, revealing an allosteric mechanism of action.
J. Ostrop, R. Zwiggelaar, M. T. Pedersen…·M. J. Oudhoff
This study develops a semi-automated intestinal organoid screening method to identify epigenetic regulators of epithelial differentiation, finding that inhibiting type I PRMTs enhances differentiation and blocks adenoma growth.