Author

T. Akama

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Harada· 1 shared A. Kikuchi· 1 shared C. Nishizawa-Harada· 1 shared C.-T. Huang· 1 shared D. L. Jarvis· 1 shared H. Eguchi· 1 shared H. Mabashi-Asazuma· 1 shared I. Kimura-Takagi· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Harada

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Author profile →

2 papers

Recent·Most cited

Recruitment of KRAS downstream target ARL4C to membrane protrusions accelerates pancreatic cancer cell invasion.

A. Kikuchi, A. Harada, S. Matsumoto, Y. Yasumizu, T. Akama, H. Eguchi

This study identifies ARL4C's role in pancreatic cancer invasion by localizing it to membrane protrusions and showing its interaction with IQGAP1 and MMP14, leading to extracellular matrix degradation and metastasis suppression via ASO.

bioRxiv · Feb 23, 2021Cancer Biology

Development of an orally-administrable tumor vasculature-targeting therapeutic using annexin A1-binding D-peptides

M. N. Fukuda, M. Nonaka, H. Mabashi-Asazuma, D. L. Jarvis, K. Yamasaki, T. Akama, M. Nagaoka, T. Sasai, I. Kimura-Takagi, Y. Suwa, T. Yaegashi, C.-T. Huang, C. Nishizawa-Harada

The paper develops an orally-administrable therapeutic using annexin A1-binding D-peptides to target tumor vasculature, showing suppression of brain tumor growth in mice.

PLOS ONE · Jan 6, 2021Peer-reviewedPharmacology & Toxicology