Author

T. B. Castro

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

G. D. Victora· 3 shared J. Pae· 2 shared L. Mesin· 2 shared S. Nakandakari-Higa· 2 shared A. Chudnovskiy· 1 shared A. Cui· 1 shared A. Efeyan· 1 shared A. K. Shalek· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersImmunology

G. D. Victora

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Identification of dendritic cell-T cell interactions driving immune responses to food

M. C. C. Canesso, T. B. Castro, S. Nakandakari-Higa, A. Lockhart, D. Esterhazy, B. S. Reis, G. D. Victora, D. Mucida

This study identifies dendritic cell subsets that drive immune responses to dietary antigens, showing that cDC1s induce regulatory T cells while cDC2s promote pro-inflammatory responses.

bioRxiv · Oct 26, 2022 · PreprintImmunology

Proximity-dependent labeling identifies dendritic cells that drive the tumor-specific CD4+ T cell response

A. Chudnovskiy, T. B. Castro, S. Nakandakari-Higa, A. Cui, C.-H. Lin, M. Sade-Feldman, B. K. Phillips, J. Pae, L. Mesin, J. Bortolatto, L. D. Schweitzer, G. Pasqual, L.-F. Lu, N. Hacohen, G. D. Victora

The paper identifies dendritic cells that present antigens to CD4+ T cells in tumor-draining lymph nodes and the tumor microenvironment using LIPSTIC-based single-cell transcriptomics.

bioRxiv · Oct 25, 2022Immunology

Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells

J. Pae, J. Ersching, T. B. Castro, M. Schips, L. Mesin, S. J. Allon, J. Ordovas-Montanes, C. Mlynarczyk, A. Melnick, A. Efeyan, A. K. Shalek, M. Meyer-Hermann, G. D. Victora

This study identifies cyclin D3 as essential for inertial cell cycling in dark zone germinal center B cells, enabling clonal expansion and linking it to potential lymphoproliferative disorders.

bioRxiv · Nov 17, 2020Immunology