Author

T. D. Patel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Coarfa· 2 shared A. G. Guzman· 1 shared A. G. Martell· 1 shared A. Nussenzweig· 1 shared A. Tovy· 1 shared B. B. de Vries· 1 shared B. W. Simons· 1 shared C.-w. Chen· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

C. Coarfa

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells

L. Zhang, J. I. Hsu, E. D. Braekeleer, C.-w. Chen, T. D. Patel, A. G. Martell, A. G. Guzman, K. Wohlan, S. M. Waldvogel, H. Urya, A. Tovy, E. Callen, R. L. Murdaugh, R. U. Richard, S. Jansen, , M. A. Goodell

This study identifies SOD1 as a synthetic lethal target in PPM1D-mutant leukemia cells through CRISPR/Cas9 screening, revealing a dysregulated redox landscape and potential therapeutic strategy.

bioRxiv · Aug 31, 2023Cancer Biology

MyoD-Cre driven alterations in K-Ras and p53 lead to a mouse model with histological and molecular characteristics of human rhabdomyosarcoma with direct translational applications

K. Nakahata, B. W. Simons, E. Pozzo, R. Shuck, L. Kurenbekova, C. Coarfa, T. D. Patel, J. T. Yustein

This paper develops a genetically engineered mouse model of rhabdomyosarcoma with molecular features similar to human RMS, providing pre-clinical tools for therapy evaluation.

bioRxiv · Jun 15, 2021 · PreprintCancer Biology