Author

T. Danhorn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. Leach· 2 shared A. J. Weisberg· 1 shared A. Tewari· 1 shared B. G. Bitler· 1 shared B. R. Corr· 1 shared B. Vestal· 1 shared C. Bailey· 1 shared C. Fuqua· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersImmunology

S. Leach

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Combination CDC-like kinase inhibition (CLK)/Dual-specificity tyrosine-regulated kinase (DYRK) and taxane therapy in CTNNB1-mutated endometrial cancer

B. R. Corr, M. R. Moroney, E. R. Woodruff, Z. L. Watson, K. R. Jordan, T. Danhorn, C. Bailey, R. J. Wolsky, B. G. Bitler

This paper evaluates SM08502, a CLK/DYRK inhibitor, as a single-agent and in combination with paclitaxel for CTNNB1-mutated endometrial cancer, showing synergistic effects and tumor volume reduction in vitro and in vivo.

bioRxiv · Apr 4, 2023 · PreprintCancer Biology

Dual adhesive unipolar polysaccharides synthesized by overlapping biosynthetic pathways in Agrobacterium tumefaciens

M. C. Onyeziri, R. Natarajan, G. G. Hardy, J. Xu, I. P. Reynolds, J. Kim, P. M. Merritt, T. Danhorn, M. E. Hibbing, A. J. Weisberg, J. H. Chang, C. Fuqua

The paper identifies genes involved in the synthesis of two distinct polysaccharides in Agrobacterium tumefaciens, essential for surface attachment.

bioRxiv · Apr 22, 2021Microbiology

Human and mouse transcriptome profiling identifies cross-species homology in pulmonary and lymph node mononuclear phagocytes

S. Leach, S. Gibbings, A. Tewari, S. Atif, B. Vestal, T. Danhorn, W. Janssen, T. Wager, C. Jakubzick

The paper compares human and mouse mononuclear phagocyte gene expression to identify homologous subtypes and marker genes, finding limited overlap in top markers between species.

bioRxiv · Apr 30, 2020Immunology

The somatically generated T cell receptor CDR3a contributes to the MHC allele specificity of the T cell receptor

P. Marrack, S. H. Krovi, D. Silberman, J. White, E. Kushnir, M. Nakayama, J. Crook, T. Danhorn, S. Leach, R. Anselment, J. Scott-Browne, L. Gapin, J. Kappler

The paper shows that the somatically generated CDR3a of T cell receptors influences MHC allele specificity during positive selection.

bioRxiv · Aug 15, 2017Immunology