Author

T. DeSouza

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. Corvera· 3 shared A. Desai· 2 shared R. Rojas-Rodriguez· 2 shared S. Y. Min· 2 shared A. Baez· 1 shared B. K. Pedersen· 1 shared C. Berg· 1 shared C. Nandrup-Bus· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCell Biology

S. Corvera

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Author profile →

3 papers

Recent·Most cited

Regulation of lipolysis by 14-3-3 proteins on human adipocyte lipid droplets.

Q. Yang, Z. Yang Loureiro, A. Desai, T. DeSouza, K. Li, H. Wang, S. M. Nicoloro, J. Solivan-Rivera, S. Corvera

This study identifies 14-3-3 proteins as regulators of lipolysis in human adipocytes by analyzing the PLIN1 interactome using proximity labeling.

bioRxiv · May 1, 2023Cell Biology

A long-non-coding RNA, LINC00473, confers the human adipose tissue thermogenic phenotype through enhanced cAMP responsiveness.

K.-V. Tran, C. Nandrup-Bus, T. DeSouza, R. Soares, N. Z. Jespersen, S. Y. Min, R. Rojas-Rodriguez, H. Willenbrock, T. Juhlin, M. C. K. Severinsen, K. Malka, B. K. Pedersen, T. Fitzgibbons, C. Scheele, S. Corvera, S. Nielsen

This study identifies LINC00473 as a key regulator of thermogenic adipocyte function, showing its role in enhancing cAMP responsiveness and mitochondrial activity.

bioRxiv · Jun 5, 2018Cell Biology

Generation of functional human adipose tissue in mice from primed progenitor cells

R. Rojas-Rodriguez, J. Lujan-Hernandez, S. Y. Min, T. DeSouza, P. Teebagy, A. Desai, H. Tessier, R. Slamin, L. Siegel-Reamer, C. Berg, A. Baez, J. Lalikos, S. Corvera

The paper shows that priming mesenchymal progenitor cells in vitro leads to the formation of functional human adipose tissue in mice, improving vascularization and reducing cell death compared to unprimed grafts.

bioRxiv · Feb 19, 2018Bioengineering