Author

T. E. T. Hughes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:protein structure prediction· 2

Frequent Co-Authors

A. Samanta· 2 shared K. W. Huynh· 2 shared R. A. Pumroy· 2 shared T. Rohacs· 2 shared V. Y. Moiseenkova-Bell· 2 shared Z. H. Zhou· 2 shared A. T. Yazici· 1 shared E. C. Fluck· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersBiophysics

A. Samanta

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2 papers

Recent·Most cited

BiophysicsbioRxivMay 24, 2019

Molecular mechanism of TRPV2 channel modulation by cannabidiol

R. A. Pumroy, A. Samanta, Y. Liu…·V. Y. Moiseenkova-Bell

This study determines the structure of TRPV2 bound to cannabidiol, revealing a unique binding site and the role of the S4-S5 linker in channel gating.

DOI 10.7554/elife.48792

cryo-EMexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivJul 31, 2018

Structural insights on TRPV5 gating by endogenous modulators

T. E. T. Hughes, R. A. Pumroy, A. T. Yazici…·V. Y. Moiseenkova-Bell

The paper determines TRPV5 structures with endogenous modulators PI(4,5)P2 and CaM, revealing their mechanisms of activation and inhibition.

DOI 10.1038/s41467-018-06753-6

cryo-EMexperimental assay

𝕏 PostBluesky