Author

T. Fair

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Organism:chicken / avian· 3 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:gene regulatory network inference· 2 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. A. Pollen· 2 shared F. Inoue· 2 shared H. Ryu· 2 shared K. S. Pollard· 2 shared S. Whalen· 2 shared A. A. PETELSKI· 1 shared A. Kriegstein· 1 shared A. Pollen· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersEvolutionary Biology

A. A. Pollen

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Author profile →

4 papers

Recent·Most cited

Single-cell proteomics reveals decreased abundance of proteostasis and meiosis proteins in advanced maternal age oocytes

S. GALATIDOU, A. A. PETELSKI, A. PUJOL, K. LATTES, L. B. LATORRACA, T. FAIR, M. POPOVIC, R. VASSENA, N. SLAVOV, M. BARRAGAN

The paper uses single-cell proteomics to show that advanced maternal age oocytes have reduced proteostasis and meiosis proteins.

bioRxiv · May 23, 2024Cell Biology

Comparative landscape of genetic dependencies in human and chimpanzee stem cells

R. She, T. Fair, N. K. Schaefer, R. A. Saunders, B. J. Pavlovic, J. S. Weissman, A. A. Pollen

The paper compares genetic dependencies in human and chimpanzee stem cells, identifying 75 species-specific genes affecting cellular proliferation and supporting the G1-phase length hypothesis in human brain evolution.

bioRxiv · Mar 19, 2023Evolutionary Biology

Three-dimensional genome re-wiring in loci with Human Accelerated Regions

K. C. Keough, S. Whalen, F. Inoue, P. F. Przytycki, T. Fair, C. Deng, M. Steyert, H. Ryu, K. Lindblad-Toh, E. Karlsson, Zoonomia Consortium, T. J. Nowakowski, N. J. Ahituv, A. A. Pollen, K. S. Pollard

The paper identifies human-specific 3D genome re-wiring in conserved loci, linking accelerated evolution to regulatory rewiring in neural progenitor cells.

bioRxiv · Oct 4, 2022Evolutionary Biology

Machine-learning dissection of Human Accelerated Regions in primate neurodevelopment

S. Whalen, F. Inoue, H. Ryu, T. Fair, E. Markenscoff-Papadimitriou, K. Keough, M. Kircher, B. Martin, B. Alvarado, O. Elor, D. L. Cintron, A. Williams, M. A. H. Samee, S. Thomas, R. Krencik, , K. S. Pollard

The paper uses machine learning to analyze human-chimpanzee variants in HARs, finding 43% affect chromatin state and 14% affect neurodevelopmental enhancer activity, with species-specific activity predicted by transcription factor footprints.

bioRxiv · Sep 28, 2022Evolutionary Biology