Structural and biochemical mechanisms of NLRP1 inhibition by DPP9
M. Huang, X. Zhang, T. G. Ann, Q. Gong, J. Wang, Z. Han, B. Wu, F. L. Zhong, J. Chai
This study identifies the structural and biochemical mechanism by which DPP9 inhibits NLRP1, preventing its activation and maintaining it in an auto-inhibited state.
bioRxiv · Aug 13, 2020Immunology