Author

T. Gamal El-Din

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

D. Jiang· 1 shared L. Tonggu· 1 shared N. Zheng· 1 shared R. Banh· 1 shared R. Pomes· 1 shared W. A. Catterall· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperPharmacology & Toxicology

D. Jiang

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivDec 28, 2020

Structural basis for voltage-sensor trapping of the cardiac sodium channel by a deathstalker scorpon toxin

D. Jiang, L. Tonggu, T. Gamal El-Din…·W. A. Catterall

This study reveals the structure of a scorpion toxin bound to a cardiac sodium channel, showing how it traps the voltage sensor and alters channel gating without opening the channel.

DOI 10.1038/s41467-020-20078-3

humanstructural biology

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