T. Gil-Gil

The Tradeoffs Between Persistence and Mutation Rates at Sub-Inhibitory Antibiotic Concentrations in Staphylococcus aureus

This study examines how sub-inhibitory antibiotic concentrations affect mutation rates and persistence in Staphylococcus aureus, showing increased mutation rates and reduced persistence.

Enteric Populations of Escherichia coli are Likely to be Resistant to Phages Due to O-Antigen Expression

The paper investigates phage resistance in E. coli due to O-antigen expression and finds that most E. coli in the gut are resistant, limiting phage impact on bacterial composition.

The Evolution of Heteroresistance via Small Colony Variants in Escherichia coli Following Long Term Exposure to Bacteriostatic Antibiotics

This study shows that long-term exposure to bacteriostatic antibiotics in E. coli leads to the emergence of small colony variants (SCVs) that confer heteroresistance, which reverts upon antibiotic removal.

Theoretical Considerations and Empirical Predictions of the Pharmaco- and Population Dynamics of Heteroresistance

This paper develops two mathematical models of heteroresistance to explore how resistance ascends and reverts during antibiotic treatment, showing that current identification methods are insufficient.

What's the matter with MICs: The contribution of nutrients and limiting resources to the pharmacodynamics of antibiotics and bacteria

This study investigates how nutrient conditions affect antibiotic pharmacodynamics by comparing MICs and bacterial growth in rich and minimal media with E. coli and eight antibiotics.

The inactivation of enzymes belonging to the central carbon metabolism, a novel mechanism of developing antibiotic resistance

This paper identifies a novel mechanism of antibiotic resistance in Stenotrophomonas maltophilia through the inactivation of central carbon metabolism enzymes, not through known resistance mechanisms like efflux or target modification.