Author

T. Hayakawa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

C. Sato· 1 shared H. Nakaoka· 1 shared H. Takeuchi· 1 shared H. Tsuboi· 1 shared I. Inoue· 1 shared I. Kato· 1 shared K. Kitajima· 1 shared K. Maenaka· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperEvolutionary Biology

C. Sato

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Author profile →

4 papers

Recent·Most cited

Thermostability and binding properties of single-chained Fv fragments derived from therapeutic antibodies

T. Tadokoro, H. Tsuboi, K. Nakamura, T. Hayakawa, R. Ohmura, I. Kato, M. Inoue, S.-i. Tsunoda, S. Niizuma, Y. Okada, S. Otsuguro, K. Maenaka

This study evaluates the thermostability and binding properties of scFv fragments from FDA-approved antibodies, showing that stable scFvs maintain antigen binding.

bioRxiv · Feb 9, 2024Bioengineering

Comparative transcriptomics shows the evolutionary origin of acoustic fat bodies through a trade-off with skull muscles in toothed whales

H. Takeuchi, T. F. Matsuishi, T. Hayakawa

This study uses comparative transcriptomics to show that acoustic fat bodies in toothed whales evolved from skull muscles through a trade-off involving fatty acid metabolism and tissue reorganization.

bioRxiv · May 25, 2023 · PreprintEvolutionary Biology

Lower promoter activity of the ST8SIA2 gene has been favored in evolving human collective brains

T. Hayakawa, M. Terahara, N. Fujito, T. Matsunaga, K. Teshima, M. Hane, K. Kitajima, C. Sato, N. Takahata, Y. Satta

The paper examines promoter activity differences in the ST8SIA2 gene between anatomically modern humans and archaic humans, finding lower promoter activity in modern humans linked to adaptation to psychosocial stress.

bioRxiv · Apr 11, 2021Evolutionary Biology

Exome sequences of toque macaques (Macaca sinica) of Sri Lanka reveal many amino acid changes

N. N. Hettiarachchi, N. Osada, T. Hayakawa, H. Nakaoka, N. Saitou, I. Inoue

This study sequences the exome of toque macaques (M. sinica) from Sri Lanka, revealing genetic differences and phylogenetic relationships with other macaque species.

bioRxiv · Sep 4, 2019 · PreprintEvolutionary Biology