Author

H. Nakaoka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 2 Evolutionary Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:imaging· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

I. Inoue· 2 shared Y. Wakamoto· 2 shared A. Coudray· 1 shared A. Soper· 1 shared D. Laurent· 1 shared D. Trono· 1 shared E. Kussell· 1 shared H. Ueda· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

I. Inoue

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Observation of persister cell histories reveals diverse modes of survival in antibiotic persistence

M. Umetani, M. Fujisawa, R. Okura, T. Nozoe, S. Suenaga, H. Nakaoka, E. Kussell, Y. Wakamoto

The paper characterizes persister cell dynamics in E. coli by tracking individual cells exposed to antibiotics, revealing diverse survival mechanisms depending on growth phase and antibiotic type.

bioRxiv · Oct 28, 2021Microbiology

In vivo CRISPRi screen reveals the differential requirement for mitochondrial respiratory chain function between in vivo and in vitro tumor growth

H. Nakaoka, N. Bennett, R. Okimoto, D. Laurent, Y. Sei, T. Bivona, J. ten Hoeve, T. Graeber, K. Nakamura, J. Nakamura

The paper uses CRISPRi to show that mitochondrial respiratory chain genes are critical for in vivo tumor growth but not for metastasis in lung cancer xenografts.

bioRxiv · Oct 3, 2021 · PreprintCancer Biology

Three-dimensional understanding of the morphological complexity of the human uterine endometrium

M. Yamaguchi, K. Yoshihara, K. Suda, H. Nakaoka, N. Yachida, H. Ueda, K. Sugino, Y. Mori, K. Yamawaki, R. Tamura, T. Ishiguro, T. Motoyama, Y. Watanabe, S. Okuda, K. Tainaka, T. Enomoto

This study uses 3D imaging to reveal the complex morphology of human endometrial glands and their pathological features in adenomyosis.

bioRxiv · May 29, 2020Pathology

Endogenous retroviruses drive KRAB zinc-finger family protein expression for tumor suppression

J. Ito, I. Kimura, A. Soper, A. Coudray, Y. Koyanagi, H. Nakaoka, I. Inoue, P. Turelli, D. Trono, K. Sato

The paper shows HERV activation in tumors upregulates KZFPs, which suppress cancer progression by downregulating cell cycle and adhesion genes, improving disease outcomes.

bioRxiv · Feb 2, 2020Cancer Biology

Exome sequences of toque macaques (Macaca sinica) of Sri Lanka reveal many amino acid changes

N. N. Hettiarachchi, N. Osada, T. Hayakawa, H. Nakaoka, N. Saitou, I. Inoue

This study sequences the exome of toque macaques (M. sinica) from Sri Lanka, revealing genetic differences and phylogenetic relationships with other macaque species.

bioRxiv · Sep 4, 2019 · PreprintEvolutionary Biology

Aging, Mortality And The Fast Growth Trade-Off Of Schizosaccharomyces pombe

H. Nakaoka, Y. Wakamoto

This study shows that replicative aging does not occur in Schizosaccharomyces pombe under favorable conditions, and protein aggregates are not a major determinant of cell fate.

bioRxiv · Apr 18, 2017Microbiology