Author

T. J. Litberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:protein folding & dynamics· 3 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:statistical model· 1

Frequent Co-Authors

S. Horowitz· 3 shared A. Son· 2 shared A. Begeman· 1 shared B. Sathyamoorthy· 1 shared J. Bourne· 1 shared R. K. R. Sannapureddi· 1 shared V. Huizar Cabral· 1 shared Z. Huang· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 18 mutual co-author links

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3 shared papersBiophysics

S. Horowitz

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Author profile →

3 papers

Recent·Most cited

G-quadruplexes rescuing protein folding

A. Son, V. Huizar Cabral, T. J. Litberg, S. Horowitz

This study shows G-quadruplexes can accelerate protein folding by rescuing kinetically trapped intermediates in E. coli, improving folding quality rather than just preventing aggregation.

bioRxiv · Sep 9, 2022Biophysics

Why are G-quadruplexes good at preventing protein aggregation?

T. J. Litberg, R. K. R. Sannapureddi, Z. Huang, A. Son, B. Sathyamoorthy, S. Horowitz

This study identifies structural factors that enable G-quadruplexes to prevent protein aggregation, offering insights into their role in disease prevention.

bioRxiv · Aug 23, 2022Biophysics

G-Quadruplexes Act as Sequence Dependent Chaperones via Protein Oligomerization

A. Begeman, T. J. Litberg, J. Bourne, Z. Xuan, S. Horowitz

This study shows nucleic acid sequences, particularly G-quadruplexes, can act as chaperones by oligomerizing with proteins to prevent aggregation, with implications for diseases like Fragile X and ALS.

bioRxiv · Nov 21, 2019Biochemistry