Author

T. K. Choueiri

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cancer & tumor microenvironment· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

S. Signoretti· 3 shared A. Sadagopan· 2 shared C. Labaki· 2 shared D. A. Braun· 2 shared E. M. Van Allen· 2 shared G.-S. M. Lee· 2 shared J. Li· 2 shared J. Nyman· 2 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

S. Signoretti

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The SLC1A1/EAAT3 Dicarboxylic Amino Acid Transporter is an Epigenetically Dysregulated Nutrient Carrier that Sustains Oncogenic Metabolic Programs

T. M. Grubb, J. Khatun, S. Matar, F. Ghandour, N. Dubasik, C. Salem, D. A. Orlando, M. G. Guenther, S. R. Martinez, P. Koochaki, J. A. Coker, C. Tang, E. Reznik, R. R. Kotecha, A. A. Hakimi, , A. A. Chakraborty

This study identifies SLC1A1/EAAT3 as an oncogenic transporter in ccRCC driven by H3K27ac, showing its role in sustaining metabolic programs and its potential as a therapeutic target.

bioRxiv · Sep 4, 2023 · PreprintCancer Biology

A genetic basis for cancer sex differences revealed in Xp11 translocation renal cell carcinoma

M. Achom, A. Sadagopan, C. Bao, F. McBride, Q. Xu, P. Konda, R. W. Tourdot, J. Li, M. Nakhoul, D. Gallant, U. A. Ahmed, J. O'Toole, D. Freeman, G.-S. M. Lee, J. Hecht, , S. R. Viswanathan

This study identifies a genetic basis for cancer sex differences in Xp11 translocation renal cell carcinoma by showing a 2:1 female:male ratio in TFE3 fusions involving the inactive X chromosome.

bioRxiv · Aug 4, 2023 · PreprintCancer Biology

Spatially aware deep learning reveals tumor heterogeneity patterns that encode distinct kidney cancer states

J. Nyman, T. Denize, Z. Bakouny, C. Labaki, B. M. Titchen, K. Bi, S. N. Hari, J. Rosenthal, N. Mehta, B. Jiang, B. Sharma, K. Felt, R. Umeton, D. A. Braun, S. Rodig, , E. M. Van Allen

The paper uses spatially aware deep learning to identify tumor heterogeneity patterns in kidney cancer, revealing distinct states associated with different histological subtypes.

bioRxiv · Jan 18, 2023Cancer Biology

The efficiency of Grignard Pure™ to inactivate airborne SARS-CoV-2 surrogate

G. Desai, G. Ramachandran, E. Goldman, A. Galione, A. Lal, T. K. Choueiri, A. Fay, W. Jordan, D. W. Schaffner, J. Caravanos, E. Grignard, G. Mainelis

This study evaluates the effectiveness of Grignard Pure™ in reducing airborne MS2 bacteriophage concentration by 2-3 logs at specific concentrations over 60-90 minutes.

bioRxiv · Aug 19, 2022 · PreprintMicrobiology

Integrative Clinical and Molecular Characterization of Translocation Renal Cell Carcinoma

Z. Bakouny, A. Sadagopan, P. Ravi, N. Y. Metaferia, J. Li, S. AbuHammad, S. Tang, T. Denize, E. R. Garner, X. Gao, D. A. Braun, L. Hirsch, J. A. Steinharter, G. Bouchard, E. Walton, , S. R. Viswanathan

This study characterizes translocation renal cell carcinoma (tRCC) through integrated clinical and molecular analysis of 152 patients, identifying key features like MiT/TFE fusions, NRF2-driven antioxidant response, and differential treatment outcomes.

bioRxiv · Apr 14, 2021Cancer Biology