Author

T. Lamb

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 3 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Approach:Bayesian inference· 1 Research Focus:cell type annotation· 1 Assay:clinical cohort / trial· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

I. Rahman· 2 shared T. Muthumalage· 2 shared A. Heringer· 1 shared A. Rativa· 1 shared D. Warrell· 1 shared E. A. Ashley· 1 shared E. Blasi· 1 shared F. Ricachenevsky· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersPharmacology & Toxicology

I. Rahman

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Nose-only Exposure to Cherry and Tobacco Flavored E-cigarettes Induced Lung Inflammation in Mice in a Sex-dependent Manner

T. Lamb, J. Meehan-Atrash, T. Muthumalage, I. Rahman

This study shows that flavored e-cigarettes caused sex-specific lung inflammation in mice, with cherry flavors increasing female inflammation and tobacco flavors increasing male inflammation.

bioRxiv · Jun 20, 2022 · PreprintPharmacology & Toxicology

Pulmonary toxicity and inflammatory response of e-cigarettes containing medium-chain triglyceride oil and vitamin E acetate: Implications in the pathogenesis of EVALI but independent of SARS-COV-2 COVID-19 related proteins

T. Muthumalage, J. Lucas, Q. Wang, T. Lamb, M. McGraw, I. Rahman

This study investigates the pulmonary toxicity and inflammatory response of e-cigarettes containing MCT and VEA, showing they induce acute lung injury without involving SARS-CoV-2 proteins.

bioRxiv · Jun 14, 2020Pharmacology & Toxicology

A Bayesian phase 2 model based adaptive design to optimise antivenom dosing: application to a dose-finding trial for a novel Russell's viper antivenom in Myanmar

J. A. Watson, T. Lamb, J. Holmes, D. Warrell, K. T. Thwin, Z. L. Aung, M. T. Nwe, F. Smithuis, E. A. Ashley

This paper proposes a Bayesian adaptive design for antivenom dose-finding trials, showing it can identify optimal doses with fewer patients than traditional methods.

bioRxiv · Feb 6, 2020Pharmacology & Toxicology

Unraveling rice tolerance mechanisms against Schizotetranychus oryzae mite infestation

G. Buffon, E. Blasi, A. Rativa, T. Lamb, R. Gastmann, J. Adamski, J. Schwambach, F. Ricachenevsky, A. Heringer, V. Silveira, M. Lopes, R. Sperotto

This study compares two rice cultivars, Puita INTA-CL and IRGA423, to identify tolerance mechanisms against Schizotetranychus oryzae mite infestation, finding IRGA423 exhibits tolerance through multiple defense-related pathways.

bioRxiv · Mar 13, 2018Plant Biology