J. Adamski

Pantothenate Kinase 4 controls efficient skeletal muscle energy substrate metabolism via acetyl-CoA

This study identifies PanK4 as a regulator of skeletal muscle energy metabolism, showing its role in acetyl-CoA regulation and metabolic flexibility.

Pharmacogenomics of GLP-1 Receptor Agonists: A genome-wide analysis of observational data and large randomized controlled trials

This study identifies genetic variants associated with glycaemic response to GLP-1 receptor agonists using observational and trial data, finding variants in GLP-1R and ARRB1 linked to HbA1c reduction.

Adaptive mitochondrial regulation of the proteasome

This study shows mitochondrial dysfunction reduces 26S proteasome assembly and activity, which can be reversed by aspartate or pyruvate supplementation.

Induction of the nicotinamide riboside kinase NAD+ salvage pathway in skeletal muscle of H6PDH KO mice

This study examines the metabolic and mitochondrial adaptations in H6PDH knockout mice, showing activation of the NRK2 NAD+ salvage pathway and its limited effect on mitigating myopathy and mitochondrial dysfunction.

Unraveling rice tolerance mechanisms against Schizotetranychus oryzae mite infestation

This study compares two rice cultivars, Puita INTA-CL and IRGA423, to identify tolerance mechanisms against Schizotetranychus oryzae mite infestation, finding IRGA423 exhibits tolerance through multiple defense-related pathways.