Cell BiologybioRxiv
BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2
A. J. Samelson, Q. D. Tran, R. Robinot…·M. Kampmann
This study identifies BRD2 as a regulator of ACE2 transcription and shows that BRD2 inhibitors block SARS-CoV-2 infection in human cells and animal models.