MAP7 family proteins regulate kinesin-1 recruitment and activation
P. J. Hooikaas, M. Martin, T. Muhlethaler, G.-J. Kuijntjes, C. A. E. Peeters, E. A. Katrukha, L. Ferrari, R. Stucchi, D. G. F. Verhagen, W. E. van Riel, I. Grigoriev, A. F. M. Altelaar, C. C. Hoogenraad, S. G. D. Rudiger, M. O. Steinmetz, , A. Akhmanova
The paper shows that MAP7 family proteins activate kinesin-1 by enhancing its microtubule binding and processivity through transient interactions.
bioRxiv · Dec 22, 2018Cell Biology