Altered hepatic metabolism mediates sepsis preventive effects of reduced glucose supply in infected preterm newborns
O. Baek, T. Muk, Z. Wu, Y. Ye, B. Khakimov, A. M. Casano, B. Gangadharan, I. Bilic, A. Brunse, P. T. Sangild, D. N. Nguyen
This study shows that reducing glucose supply during infection improves survival in preterm infants by decreasing inflammation and maintaining normoglycemia, with liver involvement in these protective effects.
bioRxiv · Sep 11, 2023Immunology