Author

O. Baek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:host-pathogen & immune response· 3 Approach:experimental assay· 2 Assay:metabolomics· 1 Organism:plant (other)· 1 Approach:statistical model· 1

Frequent Co-Authors

D. N. Nguyen· 3 shared A. Brunse· 2 shared J. Zhong· 2 shared P. T. Sangild· 2 shared Z. Wu· 2 shared A. M. Casano· 1 shared B. Gangadharan· 1 shared B. Khakimov· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersImmunology

D. N. Nguyen

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3 papers

Recent·Most cited

Reduced glucose supply during neonatal infection attenuates neurological and renal pathology via modulation of innate and Th1 immunity

J. Zhong, O. Baek, R. Doughty, B. M. Joergensen, H. E. Jensen, T. Thymann, P. T. Sangild, A. Brunse, D. N. Nguyen

This study shows that reducing glucose supply in infected preterm pigs decreases neurological and renal damage by modulating innate and Th1 immunity.

bioRxiv · May 15, 2024 · PreprintImmunology

Regulation of host metabolism and defense strategies to survive neonatal infection

Z. Wu, N. T. N. Tien, O. Baek, J. Zhong, B. Klabunde, T. T. Nguyen, N. T. H. Yen, N. P. Long, D. N. Nguyen

This study compares metabolic and defense strategies in preterm piglets infected with S. epidermidis, finding that survivors exhibit early resistance and later tolerance, linked to mitochondrial metabolism and improved survival.

bioRxiv · Feb 23, 2024Immunology

Altered hepatic metabolism mediates sepsis preventive effects of reduced glucose supply in infected preterm newborns

O. Baek, T. Muk, Z. Wu, Y. Ye, B. Khakimov, A. M. Casano, B. Gangadharan, I. Bilic, A. Brunse, P. T. Sangild, D. N. Nguyen

This study shows that reducing glucose supply during infection improves survival in preterm infants by decreasing inflammation and maintaining normoglycemia, with liver involvement in these protective effects.

bioRxiv · Sep 11, 2023Immunology