Author

T. Ngwaga

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:imaging· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

S. R. Shames· 2 shared A. G. Salberg· 1 shared A. J. Hydock· 1 shared D. Chauhan· 1 shared S. Ganesan· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

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2 shared papersMicrobiology

S. R. Shames

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2 papers

Recent·Most cited

Effector-mediated subversion of proteasome activator (PA)28αβ enhances host defense against Legionella pneumophila under inflammatory and oxidative stress conditions

T. Ngwaga, D. Chauhan, A. G. Salberg, S. R. Shames

This study shows that the L. pneumophila effector LegC4 enhances host defense against the pathogen under inflammatory and oxidative stress by subverting the host proteasome activator PA28β.

bioRxiv · Dec 27, 2021 · PreprintMicrobiology

The Dot/Icm-translocated effector LegC4 potentiates cytokine-mediated restriction of Legionella within accidental hosts.

T. Ngwaga, A. J. Hydock, S. Ganesan, S. R. Shames

This study shows that the Legionella effector LegC4 enhances cytokine-mediated restriction of Legionella replication in macrophages.

bioRxiv · Dec 11, 2018 · PreprintMicrobiology