Aminoglycoside ribosome interactions reveal novel conformational states at ambient temperature
M. E. O'Sullivan, F. Poitevin, R. G. Sierra, C. Gati, E. H. Dao, Y. Rao, F. Aksit, H. Ciftci, N. Corsepius, R. Greenhouse, B. Hayes, M. S. Hunter, M. Liang, A. McGurk, P. Mbgam, , H. DeMirci
This study examines aminoglycoside interactions with the bacterial 30S ribosome at ambient and cryogenic temperatures, revealing temperature-sensitive conformational changes and new structural states.
bioRxiv · Jul 19, 2018Biophysics