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Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
11 papers
Recent·Most cited
I. Yapici, E. H. Dao, S. Yokoi, E. Destan, E. Ayan, A. Shafiei Kamel, F. B. Ertem, C. Kulakman, M. Yilmaz, B. Tosun, H. Ciftci, A. Kepceoglu, J. A. Johnson, O. Guven, A. Ergul, , H. DeMirci
This study uses 4D crystallography to capture transient dynamics of IF1 binding to the 30S ribosomal subunit, revealing allostery and interactions during translation initiation.
bioRxiv · Oct 27, 2023 · PreprintBiophysics
N. Smith, M. Dasgupta, D. C. Wych, C. Dolamore, R. G. Sierra, S. Lisova, D. Marchany-Rivera, A. E. Cohen, S. Boutet, M. S. Hunter, C. Kupitz, F. Poitevin, F. R. Moss, A. S. Brewster, N. K. Sauter, , M. A. Wilson
The paper uses XFEL crystallography to observe conformational changes in an enzyme during catalysis, revealing ionization-linked dynamics that control catalytic activity.
bioRxiv · Aug 15, 2023Biochemistry
I. Ishigami, R. G. Sierra, Z. Su, A. Peck, C. Wang, F. Poitevin, S. Lisova, B. Hayes, F. R. Moss, S. Boutet, R. E. Sublett, C. H. Yoon, S.-R. Yeh, D. L. Rousseau
This study reveals the structural differences between the oxidized O state and the metastable OH state of cytochrome c oxidase using spectroscopy and crystallography, showing how Y244's protonation state affects proton translocation.
bioRxiv · Mar 20, 2023 · PreprintBiophysics
H. Demirci, Y. Rao, G. M. Stoffel, B. Vögeli, K. Schell, A. Gomez, A. Batyuk, C. Gati, R. G. Sierra, M. S. Hunter, E. H. Dao, H. I. Ciftci, B. Hayes, F. Poitevin, P. Li, , S. Wakatsuki
This paper investigates the structural and dynamic mechanisms of CO2 fixation by ECRs, revealing inter-subunit coupling that enables fast catalytic activity.
bioRxiv · Feb 23, 2022 · PreprintBiophysics
A. Peck, H.-Y. Chang, A. Dujardin, D. Ramalingam, M. Uervirojnangkoorn, Z. Wang, A. Mancuso, F. Poitevin, C. H. Yoon
Skopi generates diffraction images for various XFEL experiments to aid in developing feedback mechanisms for non-crystalline biomolecular structure analysis.
bioRxiv · Dec 9, 2021Biophysics
E. Ayan, B. Yuksel, E. Destan, F. B. Ertem, G. Yildirim, M. Eren, O. M. Yefanov, A. Barty, A. Tolstikova, G. K. Ketawala, S. Botha, E. H. Dao, B. Hayes, M. Liang, M. H. Seaberg, , H. DeMirci
The paper presents two apo-streptavidin structures at different temperatures and reveals cooperative allostery through water-mediated interactions.
bioRxiv · Sep 23, 2021Biophysics
S. Durdagi, C. Dag, B. Dogan, M. Yigin, T. Avsar, C. Buyukdag, I. Erol, F. B. Ertem, S. Calis, G. Yildirim, M. Orhan, O. Guven, B. Aksoydan, E. Destan, K. Sahin, , Sn
The paper determines two apo structures of SARS-CoV-2 main protease at near-physiological temperature using SFX and uses molecular simulations to analyze inhibitor binding for drug repurposing.
bioRxiv · Sep 9, 2020Biophysics
Y. Gao, G. Eskici, S. Ramachandran, F. Poitevin, A. B. Seven, O. Panova, G. Skiniotis, R. A. Cerione
The paper reports a cryoEM structure of the PDE6 complex with GTP-bound transducin, revealing its catalytic mechanism and conformational dynamics.
bioRxiv · Apr 1, 2020Biophysics
M. E. O'Sullivan, F. Poitevin, R. G. Sierra, C. Gati, E. H. Dao, Y. Rao, F. Aksit, H. Ciftci, N. Corsepius, R. Greenhouse, B. Hayes, M. S. Hunter, M. Liang, A. McGurk, P. Mbgam, , H. DeMirci
This study examines aminoglycoside interactions with the bacterial 30S ribosome at ambient and cryogenic temperatures, revealing temperature-sensitive conformational changes and new structural states.
bioRxiv · Jul 19, 2018Biophysics
E. H. Dao, F. Poitevin, R. G. Sierra, C. Gati, Y. Rao, H. I. Ciftci, F. Aksit, A. McGurk, T. Obrinski, P. Mgbam, B. Hayes, C. de Lichtenberg, F. Pardo-Avila, N. Corsepius, L. Zhang, , H. DeMirci
The paper reports an ambient-temperature X-ray crystal structure of the Thermus thermophilus 30S ribosomal decoding complex, showing consistency with cryogenic structures but with minor conformational variations.
bioRxiv · Mar 9, 2018Biophysics