Author

T. Pelaseyed

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1

Frequent Co-Authors

B. Dolan· 2 shared L. Arike· 2 shared A. Rajan· 1 shared A. S. Luis· 1 shared B. A. Vallance· 1 shared C. Dwibedi· 1 shared E. Layunta· 1 shared F. C. van de Koolwijk· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

B. Dolan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BPP43_05035 is a Brachyspira pilosicoli cell surface adhesin that weakens the integrity of the epithelial barrier during infection

A. Rajan, P. Gallego, B. Dolan, P. Patel, C. Dwibedi, A. S. Luis, S. Trillo-Muyo, L. Arike, S. van der Post, M. Simren, T. Pelaseyed

This study identifies BPP43_05035 as a Brachyspira pilosicoli adhesin that disrupts epithelial tight junctions, increasing barrier permeability during infection.

bioRxiv · Apr 6, 2024 · PreprintMicrobiology

MUC17 is an essential small intestinal glycocalyx component that is disrupted in Crohn's disease

E. Layunta, S. Javerfelt, F. C. van de Koolwijk, M. Sivertsson, B. Dolan, L. Arike, S. Thulin, B. A. Vallance, T. Pelaseyed

The paper identifies MUC17 as a critical component of the small intestinal glycocalyx that is disrupted in Crohn's disease, leading to bacterial contact and epithelial defects.

bioRxiv · Feb 8, 2024Physiology

The MYO1B and MYO5B motor proteins and the SNX27 sorting nexin regulate membrane mucin MUC17 trafficking in enterocytes

S. Jäverfelt, G. Hellsen, I. Kaji, J. R. Goldenring, T. Pelaseyed

This study identifies MYO1B, MYO5B, and SNX27 as regulators of MUC17 trafficking in enterocytes, revealing their roles in maintaining the glycocalyx and preventing bacterial attachment.

bioRxiv · Mar 6, 2023 · PreprintCell Biology