Author

I. Kaji

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

J. R. Goldenring· 3 shared A. Smith· 1 shared D. B. Lacy· 1 shared E. Kolobova· 1 shared F. C. Peritore-Galve· 1 shared G. Hellsen· 1 shared H. Oller· 1 shared J. A. Shupe· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCell Biology

J. R. Goldenring

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The MYO1B and MYO5B motor proteins and the SNX27 sorting nexin regulate membrane mucin MUC17 trafficking in enterocytes

S. Jäverfelt, G. Hellsen, I. Kaji, J. R. Goldenring, T. Pelaseyed

This study identifies MYO1B, MYO5B, and SNX27 as regulators of MUC17 trafficking in enterocytes, revealing their roles in maintaining the glycocalyx and preventing bacterial attachment.

bioRxiv · Mar 6, 2023 · PreprintCell Biology

Therapy Development for Microvillus Inclusion Disease using Patient-derived Enteroids

M. Kalashyan, K. Raghunathan, H. Oller, M.-T. Bayer, L. Jimenez, J. T. Roland, E. Kolobova, S. J. Hagen, J. D. Goldsmith, M. D. Shub, J. R. Goldenring, I. Kaji, J. R. Thiagarajah

This study uses patient-derived enteroids to model Microvillus Inclusion Disease and identifies therapeutic strategies targeting Notch signaling and chloride channels.

bioRxiv · Jan 28, 2023 · PreprintCell Biology

Toxin-mediated downregulation of absorptive ion transporters NHE3, DRA, and SGLT1 in the colon contributes to diarrhea associated with Clostridioides difficile infection.

F. C. Peritore-Galve, I. Kaji, A. Smith, L. M. Walker, J. A. Shupe, P. K. Dudeja, J. R. Goldenring, D. B. Lacy

This study shows CDI reduces NHE3, DRA, and SGLT1 in the colon, impairing ion transport and causing osmotic diarrhea.

bioRxiv · Nov 12, 2022 · PreprintPhysiology