Author

A. S. Luis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Assay:proteomics· 4 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 2 Assay:metagenomics· 2 Research Focus:gene regulatory network inference· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

C. Jin· 3 shared G. C. Hansson· 3 shared A. Basle· 2 shared A. Cartmell· 2 shared D. P. Byrne· 2 shared E. A. Yates· 2 shared E. C. Martens· 2 shared G. Vasconcelos Pereira· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

C. Jin

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

BPP43_05035 is a Brachyspira pilosicoli cell surface adhesin that weakens the integrity of the epithelial barrier during infection

A. Rajan, P. Gallego, B. Dolan, P. Patel, C. Dwibedi, A. S. Luis, S. Trillo-Muyo, L. Arike, S. van der Post, M. Simren, T. Pelaseyed

This study identifies BPP43_05035 as a Brachyspira pilosicoli adhesin that disrupts epithelial tight junctions, increasing barrier permeability during infection.

bioRxiv · Apr 6, 2024 · PreprintMicrobiology

Ruminococcus torques is a keystone degrader of intestinal mucin glycoprotein, releasing oligosaccharides used by Bacteroides thetaiotaomicron

E. Martens, S. R. Schaus, G. Vasconcelos Pereira, A. S. Luis, E. Madlambayan, N. Terrapon, M. P. Ostrowski, C. Jin, G. C. Hansson

This study identifies Ruminococcus torques as a keystone mucin-degrading bacterium that releases oligosaccharides accessible to Bacteroides thetaiotaomicron, linking its role to inflammatory bowel disease.

bioRxiv · Jan 15, 2024 · PreprintMicrobiology

Breast Milk Oligosaccharides Contain Immunomodulatory Glucuronic Acid and LacdiNAc

C. Jin, J. Lundstrom, E. Korhonen, A. S. Luis, D. Bojar

The paper identifies new milk oligosaccharide structures across nine species, revealing widespread LacdiNAc motifs and glucuronic acid-containing MOs with immunomodulatory effects.

bioRxiv · Jan 16, 2023Biochemistry

Sulfated host glycan recognition by carbohydrate sulfatases of the human gut microbiota

A. S. Luis, A. Basle, D. P. Byrne, G. S. Wright, J. London, J. Chunsheng, N. Karlsson, G. C. Hansson, P. A. Eyers, M. Czjzek, T. Barbeyron, E. A. Yates, E. C. Martens, A. Cartmell

This study analyzes carbohydrate sulfatases from Bacteroides thetaiotaomicron, correlating structural and functional data with phylogenetic and environmental analyses to understand sulfated glycan metabolism.

bioRxiv · Jul 23, 2021Biochemistry

A single bacterial sulfatase is required for metabolism of colonic mucin O-glycans and intestinal colonization by a symbiotic human gut bacterium

A. S. Luis, C. Jin, G. Vasconcelos Pereira, R. W. P. Glowacki, S. Gugel, S. Singh, D. P. Byrne, N. A. Pudlo, J. A. London, A. Basle, M. Reihill, S. Oscarson, P. Eyers, M. Czjzek, G. Michel, , E. C. Martens

This study identifies a single sulfatase essential for colonic mucin O-glycan metabolism and intestinal colonization by Bacteroides thetaiotaomicron.

bioRxiv · Nov 20, 2020 · PreprintMicrobiology