Author

T. S. Jardetzky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 2 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

B. Correia· 2 shared C. Yang· 2 shared F. Sesterhenn· 2 shared J. Bonet· 2 shared J. Cramer· 2 shared L. Abriata· 2 shared S. Georgeon· 2 shared S. Rosset· 2 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioengineering

B. Correia

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A bottom-up approach for the de novo design of functional proteins

C. Yang, F. Sesterhenn, J. Bonet, E. v. Aalen, L. Scheller, L. Abriata, J. Cramer, X. Wen, S. Rosset, S. Georgeon, T. S. Jardetzky, T. Krey, M. Fussenegger, M. Merkx, B. Correia

This paper introduces a bottom-up method for designing functional proteins tailored to complex motifs, demonstrating their use as biosensors and signaling ligands.

bioRxiv · Mar 11, 2020 · PreprintBioengineering

De novo protein design enables precise induction of functional antibodies in vivo

F. Sesterhenn, C. Yang, J. Cramer, J. Bonet, X. Wen, L. Abriata, I. Kucharska, C.-I. Chiang, Y. Wang, G. Castoro, S. Vollers, M. Galloux, R. Charles-Adrien, E. Dheilly, S. Rosset, , B. Correia

This paper introduces a de novo protein design algorithm called TopoBuilder that generates immunogens inducing precise antibody responses against respiratory syncytial virus in mice and non-human primates.

bioRxiv · Feb 14, 2020 · PreprintBioengineering

Ephrin receptor A4 (EphA4) is a new Kaposi’s sarcoma-associated herpesvirus virus entry receptor

J. Chen, Z. Zhang, S. Schaller, T. S. Jardetzky, R. Longnecker

This study identifies EphA4 as a new Kaposi’s sarcoma-associated herpesvirus entry receptor, showing it promotes viral fusion and infection better than EphA2 in HEK293T cells.

bioRxiv · Jan 3, 2019Microbiology