Author

T. Saiyed

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:imaging· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Mishra· 1 shared A. Mohan· 1 shared A. Munjal· 1 shared A. Nair· 1 shared A. P. Nair· 1 shared A. Prabhakar· 1 shared A. R. Venkitaraman· 1 shared A. S. Karumbati· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBioengineering

A. Mishra

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Author profile →

4 papers

Recent·Most cited

Multiplexed fluorescence and scatter detection with single cell resolution using on-chip fiber optics for droplet microfluidic applications

P. Gupta, A. Mohan, A. Mishra, A. Nair, N. Chowdhury, D. Balekai, K. Rai, P. Mehta, A. Prabhakar, T. Saiyed

The paper introduces OptiDrop, a platform that enables multi-parametric optical sensing of microfluidic droplets with single-cell resolution using on-chip fiber optics.

bioRxiv · May 3, 2023 · PreprintBioengineering

Therapeutic role of Filarial HSP70 in murine models of polymicrobial sepsis and H1N1 Influenza

P. Patel, S. Siddappa, B. Ravindran, T. Saiyed

A filarial HSP70 protein acts as an adjuvant therapy, improving survival in murine polymicrobial sepsis and viral infection, with nasal administration protecting against H1N1 influenza.

bioRxiv · Sep 17, 2021 · PreprintImmunology

Inhibition of HIV-1 immune modulation by small molecules targeting viral Nef-host CD80 interface

A. U. Sharma, S. Sharma, G. Arumugam, A. P. Nair, S. Ambala, G. Munagala, K. R. Yempalla, A. Munjal, S. Rajkumar, N. Kamariah, S. Ramanathan, T. Saiyed, A. R. Venkitaraman, P. P. Singh, R. Vishwakarma, , A. S. Karumbati

The paper identifies small molecules that inhibit HIV-1 Nef's down-regulation of CD80/86, restoring T-cell activation by targeting the Nef-CD80 interface.

bioRxiv · Sep 7, 2021 · PreprintMicrobiology

PDIP38 is a novel adaptor-like modulator of the mitochondrial AAA+ protease CLPXP

P. R. Strack, E. J. Brodie, H. Zhan, V. J. Schuenemann, L. J. Valente, T. Saiyed, K. Zeth, K. N. Truscott, D. A. Dougan

This paper identifies PDIP38 as a mitochondrial adaptor protein that interacts with CLPX and modulates the CLPXP protease function by stabilizing CLPX and facilitating substrate recognition.

bioRxiv · May 19, 2020 · PreprintBiochemistry