Author

T. Sharkie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Physiology· 1

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. J. Rose· 1 shared A. Jungmann· 1 shared A. Y. Chan· 1 shared A. Zota· 1 shared J. G. Okun· 1 shared J. Schumacher· 1 shared K. Schmidt· 1 shared L. Maggi· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPhysiology

A. J. Rose

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1 paper

Recent·Most cited

An endocrine-hepato-muscular metabolic cycle links skeletal muscle atrophy and hyperglycemia in type 2 diabetes

J. G. Okun, P. M. Rusu, A. Y. Chan, Y. W. Yap, T. Sharkie, J. Schumacher, S. Hille, K. Schmidt, A. Zota, A. Jungmann, L. Maggi, Y. Lee, M. Blueher, S. Herzig, M. Heikenwaelder, , A. J. Rose

This study identifies an endocrine-hepato-muscular metabolic cycle linking hyperglycemia and skeletal muscle atrophy in type 2 diabetes through dysregulated alanine metabolism and ALT enzyme activity.

bioRxiv · May 25, 2020 · PreprintPhysiology