Author

P. M. Rusu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Organism:mouse· 2 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. J. Rose· 2 shared A. Jungmann· 2 shared A. Y. Chan· 2 shared Y. W. Yap· 2 shared A. Zota· 1 shared B. C. Fam· 1 shared B. Kiens· 1 shared B. Morgan· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersPhysiology

A. J. Rose

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2 papers

Recent·Most cited

An endocrine-hepato-muscular metabolic cycle links skeletal muscle atrophy and hyperglycemia in type 2 diabetes

J. G. Okun, P. M. Rusu, A. Y. Chan, Y. W. Yap, T. Sharkie, J. Schumacher, S. Hille, K. Schmidt, A. Zota, A. Jungmann, L. Maggi, Y. Lee, M. Blueher, S. Herzig, M. Heikenwaelder, , A. J. Rose

This study identifies an endocrine-hepato-muscular metabolic cycle linking hyperglycemia and skeletal muscle atrophy in type 2 diabetes through dysregulated alanine metabolism and ALT enzyme activity.

bioRxiv · May 25, 2020 · PreprintPhysiology

Restriction of essential amino acids dictates the systemic response to dietary protein dilution

Y. W. Yap, P. M. Rusu, A. Y. Chan, B. C. Fam, A. Jungmann, S. M. Solon-Biet, C. K. Barlow, D. J. Creek, C. Huang, R. B. Schittenhelm, B. Morgan, D. Schmoll, B. Kiens, M. D. Piper, M. Heikenwalder, , A. J. Rose

This study shows that restricting essential amino acids, not non-essential ones, drives systemic metabolic responses to dietary protein dilution and genetic amino acid transport loss.

bioRxiv · Nov 20, 2019 · PreprintPhysiology