Author

T. Shiomi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:behavioral assay· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Ota· 1 shared C. Talbot Cooper· 1 shared H. Kusano· 1 shared H. Yoshitaka· 1 shared H. Zeng· 1 shared J. D. Best· 1 shared K. Ikegami· 1 shared K. Koatsu· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPhysiology

A. Ota

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2 papers

Recent·Most cited

Low-dose cytokine immunotherapy of solid cancers enabled by phagocytic-competent protein co-crystals

M. H. Jones, N. E. Quispe Calla, R. Smith, C. Talbot Cooper, S. Rudge, H. Kusano, T. Shiomi, Y. Ishikawa, H. Zeng, J. D. Best

This study demonstrates that PODS-IL-2, a phagocytic-competent protein co-crystal, can deliver low-dose IL-2 effectively for treating melanoma and renal cell carcinoma with improved tolerability.

bioRxiv · Apr 6, 2023 · PreprintCancer Biology

A mouse model of insomnia with sleep apnea

S. Masubuchi, T. Yano, K. Koatsu, K. Ikegami, W. Nakamura, A. Ota, S. Karnan, K. Takeuchi, H. Yoshitaka, T. Todo, T. Shiomi

This paper develops a mouse model of comorbid insomnia and sleep apnea (COMISA) by inducing daytime hypoxia, showing a down-and-up activity response linked to sleepiness and insomnia.

bioRxiv · Aug 16, 2022 · PreprintPhysiology