Direct Relationship between Protein Expression and Progeny Yield of Herpes Simplex Virus 1 Unveils a Rate-limiting Step for Virus Production
M. Nobe, Y. Maruzuru, K. Takeshima, F. Maeda, H. Kusano, R. Yoshimura, T. Nishiyama, H. Park, Y. Kozaki, S. Iwami, N. Koyanagi, A. Kato, T. Natsume, S. Adachi, Y. Kawaguchi
This study identifies a direct relationship between viral protein expression and progeny yield in herpes simplex virus 1, revealing DNA cleavage/packaging as a rate-limiting step for virus production.
bioRxiv · Jun 7, 2023 · PreprintMicrobiology