Author

T. Van Agtmael

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Granata· 1 shared A. J. Garcia· 1 shared C. Vilain· 1 shared D. W. Zhou· 1 shared E. N. Mpoyi· 1 shared H. S. Markus· 1 shared K. Horsburgh· 1 shared K. Kadler· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

A. Granata

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases in extracellular matrix abnormalities

M. Al-Thani, M. Goodwin-Trotman, S. Bell, K. Patel, L. K. Fleming, C. Vilain, M. Abramowicz, S. M. Allan, T. Wang, Z. Cader, K. Horsburgh, T. Van Agtmael, S. Sinha, H. S. Markus, A. Granata

This paper develops a human iPSC model of COL4A1/A2 small vessel disease, showing that MMP inhibition rescues ECM abnormalities and mural cell defects.

bioRxiv · Feb 23, 2023 · PreprintCell Biology

Material-Driven Fibronectin Assembly Rescues Matrix Defects due to Mutations in Collagen IV in Fibroblasts

E. N. Mpoyi, M. Cantini, Y. Y. Sin, L. Fleming, D. W. Zhou, M. Costell, Y. Lu, K. Kadler, A. J. Garcia, T. Van Agtmael, M. Salmeron-Sanchez

This study shows that fibronectin-coated biomaterials can rescue matrix and cellular defects in fibroblasts with collagen IV mutations.

bioRxiv · Jan 6, 2020Bioengineering