Author

T. Van Brussel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

D. Lambrechts· 2 shared J. Fernandez-Garcia· 2 shared J. Van Elsen· 2 shared P. Carmeliet· 2 shared S.-M. Fendt· 2 shared A. A. Pane· 1 shared A. Aurora· 1 shared C. Jauset· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

D. Lambrechts

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

CD8+ T Cell Metabolic Rewiring Defined by Single-Cell RNA-Sequencing Identifies a Critical Role of ASNS Expression Dynamics in T Cell Differentiation

J. Fernandez-Garcia, F. Franco, S. Parik, A. A. Pane, D. Broekaert, J. Van Elsen, I. Vermeire, T. Van Brussel, R. Schepers, E. Modave, T. Karakach, P. Carmeliet, D. Lambrechts, P.-C. Ho, S.-M. Fendt

This study uses scRNA-seq to analyze CD8+ T cell metabolic dynamics during activation and differentiation, identifying ASNS expression dynamics as critical for determining T cell fate.

bioRxiv · Jul 27, 2021Immunology

Heterogeneity in PHGDH protein expression potentiates cancer cell dissemination and metastasis

M. Rossi, G. Doglioni, L. Bornes, D. Broekart, M. Planque, J. Fernandez-Garcia, G. Rinaldi, J. Van Elsen, D. Nittner, C. Jauset, F. Rizzollo, C. Riera Domingo, M. Orth, L. E. Dobrolecki, T. Van Brussel, , S.-M. Fendt

This study identifies PHGDH protein expression heterogeneity as a driver of breast cancer metastasis by altering metabolic pathways and promoting dissemination.

bioRxiv · Jan 24, 2021Cancer Biology