Author

T.-Y. Chiu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

H.-C. Tsai· 2 shared J.-C. Liao· 2 shared A. M. Jadhav· 1 shared C. G. Parker· 1 shared C. Liu· 1 shared C.-C. Fan· 1 shared C.-J. Yu· 1 shared C.-T. Lin· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

H.-C. Tsai

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Chemoproteomics-guided Development of SLC15A4 Inhibitors with Anti-inflammatory Activity

D. C. Lazar, W. W. Wang, T.-Y. Chiu, W. Li, A. M. Jadhav, J. M. Wozniak, N. Gazaniga, J. Teijaro, C. G. Parker

The paper develops first-in-class SLC15A4 inhibitors that suppress endosomal TLR and NOD signaling in immune cells and show anti-inflammatory effects in vivo and clinical settings.

bioRxiv · Oct 7, 2022Immunology

INPP5E regulates CD3ζ enrichment at the immune synapse by phosphoinositide distribution control

T.-Y. Chiu, F.-H. Yang, W. M. Chong, H.-C. Tsai, W.-J. Wang, J.-C. Liao

This study shows INPP5E regulates CD3ζ localization at the immune synapse by controlling phosphoinositide distribution, affecting TCR signaling and IL-2 secretion.

bioRxiv · Jan 6, 2021Cell Biology

Epigenetic therapy remodels the immune synaptic cytoskeleton to potentiate cancer susceptibility to γδ T cells

R. R. Weng, H.-H. Lu, C.-T. Lin, C.-C. Fan, R.-S. Lin, T.-C. Huang, S.-Y. Lin, Y.-J. Huang, Y.-H. Juan, Y.-C. Wu, Z.-C. Hung, C. Liu, X.-H. Lin, W.-C. Hsieh, T.-Y. Chiu, , H.-C. Tsai

DNA methyltransferase inhibitors enhance γδ T cell-mediated lung cancer killing by remodeling immune synaptic cytoskeletal networks.

bioRxiv · Apr 30, 2020 · PreprintCancer Biology