A rat model of cirrhosis with well-differentiated hepatocellular carcinoma induced by thioacetamide
Zhiping Hu, Takeshi Kurihara, Yiyue Sun, Zeliha Cetin, Rodrigo M. Florentino, Lanuza A. P. Faccioli, Zhenghao Liu, Bo Yang, Alina Ostrowska, Joseph D. Locker, Alejandro Soto-Gutierrez, Evan R. Delgado
This study develops a rat model of cirrhosis-induced hepatocellular carcinoma using thioacetamide, showing fibrosis, altered liver architecture, and increased AFP levels.
bioRxiv · Apr 18, 2024Pathology