Suppression of hepatic amino acid catabolism by the human-specific lncRNA hLMR1
Marcos E Jaso-Vera, Shohei Takaoka, Lanuza A.P. Faccioli, Zhiping Hu, Alejandro Soto–Gutiérrez, Xiangbo Ruan
This study identifies hLMR1, a human-specific lncRNA, as a suppressor of hepatic amino acid catabolism and ureagenesis, linking its dysregulation to metabolic dysfunction in MAFLD.
bioRxiv · Nov 8, 2025 · PreprintMolecular Biology