NeuroscienceDisease Models & MechanismsPeer-reviewed
Neuroinflammation induces nerve growth factor dependent nociceptor sensitisation in a neonatal rodent model of platinum-based chemotherapy induced neuropathic pain
Marlene E. Da Vitoria Lobo, Lydia D. Hardowar, Tameille Valentine…·Richard P. Hulse
This study shows cisplatin induces NGF-mediated neuroinflammation and nociceptor sensitisation in a neonatal rodent model of chemotherapy-induced neuropathic pain, identifying NGF/TrkA as a potential therapeutic target.
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