Marlene E. Da Vitoria Lobo

Neuroinflammation induces nerve growth factor dependent nociceptor sensitisation in a neonatal rodent model of platinum-based chemotherapy induced neuropathic pain

This study shows cisplatin induces NGF-mediated neuroinflammation and nociceptor sensitisation in a neonatal rodent model of chemotherapy-induced neuropathic pain, identifying NGF/TrkA as a potential therapeutic target.

Quantifying spinal cord vascular permeability in the mouse using intravital imaging

The paper uses intravital imaging in mice to study spinal cord vascular permeability and function in real time.

Hypoxia induced carbonic anhydrase mediated dorsal horn sensory neuron activation and induction ofneuropathic pain

The paper shows that hypoxia in the spinal dorsal horn, caused by vascular issues, activates sensory neurons and leads to neuropathic pain, which can be reversed by inhibiting carbonic anhydrase.