Author

Mark J. Paul‐Clark

Nottingham Trent UniversityORCID 0009-0005-8686-1374Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Richard P. HulseiD· 2 shared Benjamin DickinsiD· 1 shared Charlotte Guest· 1 shared Dhyana Sharma· 1 shared Jack Corbett· 1 shared Lucy Tomblin· 1 shared Lydia D. HardowariD· 1 shared Marlene E. Da Vitoria LoboiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Richard P. HulseORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 24, 2024

Connexin 43 mediated mitochondrial transfer prevents cisplatin induced sensory neurodegeneration.

Rebecca Owen, Jack Corbett, Mark J. Paul‐Clark, Richard P. Hulse

This study shows that connexin 43-mediated mitochondrial transfer from monocytes to damaged sensory neurons prevents cisplatin-induced neurodegeneration.

DOI 10.1101/2024.10.24.620120

mousebulk RNA-seq

𝕏 PostBluesky

NeuroscienceDisease Models & MechanismsPeer-reviewedOct 21, 2024

Neuroinflammation induces nerve growth factor dependent nociceptor sensitisation in a neonatal rodent model of platinum-based chemotherapy induced neuropathic pain

Marlene E. Da Vitoria Lobo, Lydia D. Hardowar, Tameille Valentine…·Richard P. Hulse

This study shows cisplatin induces NGF-mediated neuroinflammation and nociceptor sensitisation in a neonatal rodent model of chemotherapy-induced neuropathic pain, identifying NGF/TrkA as a potential therapeutic target.

14 citations

mouseexperimental assay

𝕏 PostBluesky