Id1 Promotes Clonal Hematopoiesis in Mice with Tet2 Loss of Function
Shweta Singh, Kristbjorn O. Gudmundsson, Tanmoy Sarkar, Brad L. Jakubison, Holly M. Morris, Sandra Sczerba Burkett, Baktiar O. Karim, Gary T. Pauly, Dina M. Sigano, Joel P. Schneider, Lino Tessarollo, Jonathan R. Keller
Genetic ablation of Id1 in Tet2-/- mice reduces clonal hematopoiesis by increasing CDKI expression, apoptosis, senescence, and differentiation while decreasing cell growth.
Science Advances · Aug 29, 2025Peer-reviewedCancer Biology