Author

Jonathan R. Keller

Frederick National Laboratory for Cancer ResearchORCID 0000-0001-9767-0067Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Kristbjorn O. GudmundssoniD· 2 shared Baktiar O. KarimiD· 1 shared Ben TitleiD· 1 shared Bjorg GudmundsdottiriD· 1 shared Brad L. JakubisoniD· 1 shared Dina M. SiganoiD· 1 shared Galya Monderer‐Rothkoff· 1 shared Gary T. PaulyiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Kristbjorn O. GudmundssonORCID

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2 papers

Recent·Most cited

Cancer BiologyScience AdvancesPeer-reviewedAug 29, 2025

Id1 Promotes Clonal Hematopoiesis in Mice with Tet2 Loss of Function

Shweta Singh, Kristbjorn O. Gudmundsson, Tanmoy Sarkar…·Jonathan R. Keller

Genetic ablation of Id1 in Tet2-/- mice reduces clonal hematopoiesis by increasing CDKI expression, apoptosis, senescence, and differentiation while decreasing cell growth.

3 citations

mousebulk RNA-seq

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GeneticsNature CommunicationsPeer-reviewedNov 17, 2020

Pogz deficiency leads to abnormal behavior, transcription dysregulation and impaired cerebellar physiology

Reut Suliman-Lavie, Ben Title, Yahel Cohen…·Sagiv Shifman

This study shows that Pogz deficiency in mice causes brain abnormalities, transcription dysregulation, and cerebellar dysfunction resembling ASD features in humans.

58 citationstop 3%

mouseexperimental assay

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