PINK1 is a target of T cell responses in Parkinson's disease
Gregory P. Williams, Antoine Freuchet, Tanner Michaelis, April Frazier, Ngan K. Tran, João Rodrigues Lima-Júnior, Elizabeth Jane Phillips, Simon Alexander Mallal, Irene Litvan, Jennifer G. Goldman, Roy N. Alcalay, John Sidney, David Sulzer, Alessandro Sette, Cecilia S. Lindestam Arlehamn
The paper identifies PINK1 as an autoantigen targeted by T cells in Parkinson's disease, with reactivity predominantly observed in male patients.
Journal of Clinical Investigation · Dec 17, 2024Peer-reviewedImmunology